What You Need to Know About Pimobendan (Vetmedin, Cardisure)

What You Need to Know About Pimobendan (Vetmedin, Cardisure)

What is pimobendan? Why was it prescribed to my pet?

Pimobendan is a medication prescribed to slow the progression of several heart diseases, most commonly mitral valve disease (MVD). Pimobendan primarily works on the heart to increase its pumping ability. It also widens blood vessels to reduce blood pressure and the workload on the heart.
Pimobendan has only been formally evaluated in dogs. Although it has been used safely in other animals, this should only be performed under close supervision from a veterinarian.

What forms are available?

Pimobendan is available in tablet, capsule and liquid forms, which are given by mouth. If possible, pimobendan should be given on an empty stomach at least 1 hour before food.
Always follow your veterinarian’s instructions when giving medication to your pet.
•    Tablets
o    Vetmedin 1.25mg, 5mg
o    Cardisure 1.25mg, 2.5mg, 5mg 
o    Generics (1), (2), (3)
•    Capsules
o    Vetmedin 2.5mg, 5mg
•    Liquids
o    Vetmedin 3.5mg/ml

What side effects are there?

Some dogs may experience lethargy, appetite loss, vomiting or diarrhoea on this medication. These are usually not a cause for concern unless they are severe, worsen, or continue over a long period of time. 
Contact your veterinarian if you notice any of the following:
•    Skin rash
•    Coughing or wheezing
•    Breathing difficulties
•    Weakness, collapse or fainting
•    Bloated belly

When should pimobendan be used very carefully?
Your veterinarian may take additional precautions if your pet:
•    Is under 6 months of age
•    Was born with their heart condition
•    Has an uncontrolled irregular heart rhythm
•    Is pregnant or nursing
•    Has diabetes or other serious disease
•    Is taking certain medications for irregular heart rhythm or high blood pressure
Precautions may include measures such as closer monitoring or adjustments to medication doses. For advice specific to your pet, please consult your veterinarian.

When should pimobendan not be used?

Your pet should not receive pimobendan if they:
•    Are allergic to it
•    Do not have heart disease
•    Have early-stage heart disease (without abnormal findings on imaging)
•    Have a heart disease that may be worsened by pimobendan

What monitoring is required for pets on pimobendan?

It is important to take your veterinarian’s advice and bring your pet for rechecks as needed.
Depending on your pet’s underlying condition, your veterinarian may wish to monitor:
•    Blood pressure 
•    Your pet’s activity level
•    The number of breaths your pet takes per minute while asleep

Storage and safety

Keep all medications out of reach of children and pets. Pimobendan should be stored at room temperature in a cool, dry place away from light.
Give this medication for as long as your veterinarian specifies and do not discontinue it without first consulting them. If you miss a dose, give it as soon as possible, but if it is near the time of your pet’s next scheduled dose, skip the missed dose and give the scheduled dose. Afterwards, return to your pet’s regular dosing regimen.
Never give a double dose, even if you miss a dose. Contact your veterinarian if you know or suspect that your pet has received an overdose.